Greetings dear reader, in this article we will talk about the different types of medications most used for gastritis in adults and how they can help you effectively. It is important that you know them and know how to differentiate them, since there are a wide variety of them on the market and the pharmacological treatment that they prescribe will vary from the type of gastritis that you present.
The harmonious relationship between gastric juices , the mucous layer and the stomach epithelium is designed so that the stomach fulfills its digestive function of absorption and protection, without causing damage.
Multiple causal factors such as stress, alcohol, coffee, poor diet, medications, h. pylori, can alter this relationship, causing an imbalance, in which the acidic pH of the gastric content ends up damaging the stomach epithelium.
To treat this imbalance there is a range of drugs for gastritis that are used according to the original cause, whether for stomach problems, gastroesophageal reflux, stomach ulcers or dyspepsia, a correct anamnesis is required to identify the causative factor; to be able to choose the drug to be prescribed.
Next, I will explain the types of medications most used to treat heartburn or pills for heartburn, which will help combat this disorder, however the abuse of these medications can also cause or worsen the problem of gastritis.
Types of Medicines for Gastritis
Among the over-the-counter (OTC, over-the-counter) gastritis medicines, patients can choose from: antacids, H2 blockers, and proton pump inhibitors (PPIs).
Depending on the frequency of symptoms or type of inflammation presented, the following drugs can be distinguished:
- Sudden: They are treated with antacids (when stomach upset occurs after a night of alcohol, or after heavy meals).
- Recurrent: H2 blockers are used that I will explain later (in periods of stress or when presenting reflux).
- Chronic: Proton pump inhibitors are used with more powerful and lasting effects, allowing the mucosa to recover.
The mechanism of action, active principles, commercial options, adverse effects and consequences of long-term use of these drugs will be detailed below.
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They are weak bases that neutralize gastric acid already secreted, by raising stomach pH. They act immediately but with less prolonged effects. They fight the symptoms of gastritis temporarily, but they are not recommended as the main treatment to eliminate it.
Antacids should contain the following compounds:
- Sodium bicarbonate.
- Calcium carbonate.
- Magnesium and aluminum hydroxide.
Among the commercial options are:
- Picot Grape Salt.
- Alka Seltzer.
- Melox Plus.
- Pepto bismol.
They can be found in syrups (magnesium), effervescent pills for the stomach and some in chews. Antacids are drugs that are widely used for being a good medicine for gastritis, they help heartburn, they are practical and the relief that is achieved is effective and temporary.
When the hydrochloric acid HCL in the stomach reacts with the antacid, they form water and a salt that cannot be absorbed, which is defecated. In the case of sodium bicarbonate, in addition to H2O and salts, carbon dioxide CO2 is also produced, which is eliminated in the form of belching.
The adverse effects are caused by the by-products of the reaction, these vary depending on the antacid used; calcium and aluminum salts cause constipation, while magnesium salts are laxatives.
This type of medicine for gastritis acts at the level of stomach acid production, decreasing the secretion of hydrochloric acid by the parietal cells of the stomach, by blocking histamine receptors in a competitive way, preventing them from being stimulated by the histamine produced by ECL enterochromaffin cells .
They do not relieve symptoms immediately, their effect takes about an hour, but they relieve for a longer period of time than antacids (1 day).
Among the H2 blockers we have:
- Ranitidina (Zantac, Tritec, Walzan).
- Famotidina (Pepcid, Clamicid, Fluxid).
- Cimetidina (Tagamet HB, nizatidina, Axid).
These drugs cross the placenta and are also secreted into breast milk, therefore, in these two conditions, their use should be anticipated to the medical consultation. Side effects are rare, the most likely being headaches when consuming Famotidine and Ranitidine.
Proton pump inhibitor (PPI) medications
They are the drugs with the highest demand on the market to combat heartburn and chronic gastritis (caused by H. pylori). They replaced H2 blockers thanks to their longer effect (2 to 3 days). These begin to relieve symptoms in 30 minutes to 2 hours.
They work by decreasing the secretion of HCL by irreversibly blocking the proton pump (H + / K + ATPase). This enzyme secretes H + ions into the stomach lumen, raising their concentration, lowering the pH.
Among the active ingredients and brands are:
- Omeprazol (Prilosec OTC, Omesec, Losec).
- Pantoprazole (Protonix).
- Lansoprazol (Prevacid 24 HR).
- Esomeprazole (Nexium).
These drugs cross the blood-brain barrier so their side effects are : headache, fatigue, vertigo, nausea.
Gastritis Medications – Recommendations
Self-medicating is not recommended, because the risk is very high, and you must also be very careful when selecting the appropriate treatment.
Medicines for gastritis, without a doubt, become very effective in reducing any symptoms that may arise from this annoying disease, however, as it is considered a chemical treatment, it is always recommended that it be designed and prepared by a doctor. .
You must always abide by what they tell you, respecting the hours and takes to achieve good results in your health. Antibiotics should always be taken at the same time every day, in the doses that were suggested by the doctor. Avoid ingesting alcoholic beverages or other types of medications that have not been prescribed because they can alter the result.
Let’s not forget that the solution to end this problem is in our hands, that is why routine check-ups and health care are recommended, which will not depend on the drugs to be consumed, but on ourselves.
Thank you for reading this informative article, keep visiting us so that you are always informed of everything related to gastritis. You can continue reading other articles of great importance on my blog.