Progesterone Deficiency: A Cause of Hashimoto’s Thyroiditis?

Everything in our body is designed to be balanced by nature. This enormously complex system, which we call the human organism, needs a balanced relationship between the immune cells, the nutrients or the hormones at all times and under all circumstances, to name the most important examples.

If this is not the case, one speaks of an imbalance, which is not only unpleasant and disturbing in a variety of ways, but can also force certain clinical pictures. Hashimoto patients can surely sing a song about it. But what influence does a progesterone deficiency have on Hashimoto’s thyroiditis ?

What exactly is progesterone?

Progesterone is a steroid hormone, the most important representative of the progestins, belongs to the group of sex hormones and is in fact the antagonist to estrogen , whereby the two are very finely tuned to one another in their interaction.

It is therefore an endogenous hormone, which is particularly active in the second half of the women’s cycle and causes an increased basal body temperature. It is formed in the ovaries (yellow bodies) and has the task of preparing the uterine lining for the implantation of an egg cell.

In addition, this hormone is largely responsible for forming collagen cells and strengthening bones . But it also affects the immune system, counteracts depressive moods, stimulates the libido and supports the action of thyroid hormones .

How do progesterone deficiency and estrogen dominance manifest themselves?

If your body no longer produces enough progesterone, there will naturally be an imbalance in the hormonal balance and estrogen will begin to dominate. In addition, the effect of the thyroid hormones is reduced , since the thyroid hormones T3 and T4 can no longer be properly utilized by the organs and body cells due to the estrogen dominance that has arisen.

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This in turn leads to an underactive thyroid despite good hormone production by the thyroid gland. In such a case, one should address the progesterone deficiency or estrogen dominance and not primarily treat the thyroid gland.

What are the symptoms of a progesterone deficiency?

You can recognize a lack of progesterone by the following symptoms, among others:

  • mild irritability
  • breast tenderness
  • water retention
  • weight gain
  • Muscle aches
  • mood swings
  • increasingly depressed perception and behavior
  • heavier and longer menstrual bleeding
  • severe period pains
  • headache
  • unfulfilled desire to have children
  • Dizzy spells and inexplicable circulatory problems
  • loss of libido
  • lack of concentration
  • sleep disorders
  • dry mucous membranes
  • tingling on the skin
  • frequent cyst formation or fibroids
  • increased symptoms during menopause
  • cardiac arrhythmias
  • iron deficiency
  • unfounded panic
  • endometriosis
  • PMS (Premenstrual Syndrome)

What causes lead to progesterone deficiency / estrogen dominance?

A lack of progesterone always occurs due to a weakness of the corpus luteum. A complete corpus luteum cannot develop if the follicles have not matured sufficiently and an egg cell has not been able to form as a result.

The following circumstances often lead to this:

  • menopause
  • estrogens in food
  • Xenoestrogens in lacquers, paints, exhaust fumes and pesticides
  • psychotropic drugs
  • Antidiabetics
  • Wrong diet
  • chronic stress
  • lack of exercise
  • light mangle
  • Dysfunction of the ovaries
  • insulin resistance
  • Smoking, drug and alcohol use
  • mineralstoffmangel

More on the subject:

What is the relationship between Hashimoto’s thyroiditis and progesterone deficiency?

In general, hormones can promote or suppress autoimmune diseases and inflammatory processes in the body. The connection between Hashimoto’s thyroiditis and progesterone becomes clear, especially in women who are deficient in this hormone.

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For example, while the concentration of this hormone increases continuously during pregnancy and thus has a positive effect on the course of Hashimoto’s thyroiditis, after childbirth there is often a very sharp drop in the progesterone level and acute flare-ups of inflammation in the thyroid gland.

Anyone who has not yet developed Hashimoto’s thyroiditis clearly belongs to a risk group. Because the associated estrogen dominance is a cause for the outbreak of the autoimmune disease in 80 percent of women .

Conversely, this means that the lack of progesterone can be regarded as the cause of Hashimoto’s thyroiditis . Because the sex hormone has a massive impact on your immune system, affects the thyroid gland, normally inhibits inflammation and stops the excessive immune reactions that occur in the autoimmune disease.

If your progesterone level is disturbed at one point in your life or permanently too low, this promotes the misguided defense reaction in your body.

How do you diagnose progesterone deficiency?

If your doctor has reasonable grounds to suspect a progesterone deficiency, he will arrange for a progesterone test. In this test, both hormones, progesterone and estrogen, are determined in the saliva or in the blood serum.

This test must be carried out between the 19th and 21st day of the cycle and can be supported by recording a basal body temperature curve.

What are the normal values ​​for progesterone?

The normal values ​​for progesterone in the blood serum are cycle-dependent in women and are not subject to daily rhythms:

follicular phase <1.0 ng/ml
periovulatorisch <3.0 ng/ml
Lutealphase > 10 ng/ml
postmenopausal <0.3 ng/ml

How can you compensate for a lack of progesterone?

In order to be able to restore the natural balance between estrogen and progesterone, a targeted therapy is required, in which vitamins and micronutrients must be supplied.

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Holistic therapy and treatment is recommended in order to permanently improve or subside your symptoms with regard to Hashimoto’s thyroiditis . There are various preparations for this. Ranging from progesterone ointments and creams to capsules.

In the case of the ointments, nature-identical progesterone ointments made from the yam root have proven themselves, which are applied to the inside of the upper arm in the evening. These ointments and creams are usually mixed with 3.5 or 10% active ingredient.

If the progesterone deficiency in Hashimoto’s thyroiditis is also compensated for with such an ointment, the anti-TPO thyroid antibodies decrease within a few months .

In addition, the treatment of a progesterone deficiency should not only be treated with conventional medical preparations, but also a special form of nutrition should be considered. This should consist of foods that contain plant hormones and lots of diosgenin, which closely resembles human progesterone.

Foods high in progesterone include:

  • Wheat, buckwheat, almonds, rice, sesame, peanuts, flaxseed
  • Garlic, Lettuce, Horseradish, Yarrow
  • Coffee, black tea, cocoa
  • Pineapple, Dates, Lemons, Coconut, Strawberries, Papaya
  • Beans, peas, corn, asparagus, tomatoes, carrots, cucumbers

Light therapy can also be very helpful in treating progesterone deficiency. But the effects of classic homeopathy, phytotherapy, psychotherapy and learning stress management methods should not be underestimated.

Because these support the treatments by the doctor and have a very positive effect on you, your body and your mind.


Women in particular are affected by a lack of progesterone in certain phases of life. It is not uncommon for this to be the trigger for Hashimoto’s thyroiditis or to have a negative impact on Hashimoto’s thyroiditis.

This particular hormone deficiency should definitely be corrected , because it can be particularly responsible for the fact that inflammation develops, antibodies against the thyroid gland increase and the symptoms of the autoimmune disease increase.

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